Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730336 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HTTKDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9729932 | 0.81 | MCL1 (0.41) | ALDH1A1KDM4EKMT2AMEN1MAPK1 | |
| SCHEMBL7332932 | 0.81 | MTNR1A (0.46) | ALDH1A1HTTMAPTHSD17B10 | |
| SCHEMBL31486626 | 0.78 | HTR2A (0.43) | ALDH1A1HTTMAPK1GAA | |
| SCHEMBL7326609 | 0.72 | PDE4A (0.41) | KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9730335 | 0.72 | PDE4A (0.41) | KDM4ESMN1; SMN2 | |
| SCHEMBL9090622 | 0.69 | CYP1A2 (0.62) | ALDH1A1HSD17B10USP2HPGD | |
| SCHEMBL9088979 | 0.69 | CYP1A2 (0.57) | ALDH1A1HSD17B10USP2HPGD | |
| Formic Acid SCHEMBL31487171 | 0.69 | GAA (0.39) | ALDH1A1KMT2AMAPK1MAPTGAA | |
| Fumaric Acid SCHEMBL9870199 | 0.68 | CYP1A2 (0.55) | ALDH1A1KDM4EMAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393766-A2 | New 3-N substituted carbamoyl-indole derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-10-24 | — | — | EP | disclosed |