Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9730335 | 0.99 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DHTR3E | |
| SCHEMBL7332932 | 0.84 | MTNR1A (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7326237 | 0.79 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7431353 | 0.76 | HTR3E (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7329638 | 0.73 | KDM4E (0.57) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7364339 | 0.72 | HTR3A (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7325776 | 0.72 | ALDH1A1 (0.48) | KDM4ESMN1; SMN2 | |
| SCHEMBL9730336 | 0.72 | ALDH1A1 (0.37) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9879687 | 0.72 | HTR3A (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6334232 | 0.71 | KDM4E (0.44) | PDE4APDE4BPDE4CPDE4DCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393766-A2 | New 3-N substituted carbamoyl-indole derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-10-24 | — | — | EP | disclosed |