Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 17/20 | 0.66 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.57 |
| ▸ | XRCC6 | P12956 | 2/20 | 0.54 |
| ▸ | XRCC5 | P13010 | 2/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326777 | 0.81 | PRKDC (0.67) | PRKDCPIK3CDXRCC6XRCC5PIK3CB | |
| SCHEMBL7327543 | 0.80 | PRKDC (0.72) | PRKDCPIK3CDXRCC6XRCC5PIK3CB | |
| SCHEMBL21154013 | 0.80 | NPC1 (0.50) | PRKDCPIK3CG | |
| SCHEMBL21153991 | 0.77 | FAAH (0.55) | — | |
| SCHEMBL30611207 | 0.77 | FAAH (0.55) | — | |
| SCHEMBL7329165 | 0.77 | PRKDC (0.67) | PRKDCPIK3CDXRCC6XRCC5PIK3CB | |
| SCHEMBL7315961 | 0.76 | PRKDC (0.66) | PRKDCPIK3CDXRCC6XRCC5PIK3CB | |
| SCHEMBL7320037 | 0.76 | PRKDC (0.66) | PRKDCPIK3CDXRCC6XRCC5PIK3CB | |
| SCHEMBL7323875 | 0.75 | PRKDC (0.71) | PRKDCXRCC6XRCC5 | |
| SCHEMBL7321603 | 0.70 | PRKDC (0.58) | PRKDCPIK3CDXRCC6XRCC5PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | claimed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | claimed |
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |