Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 8/20 | 0.67 |
| ▸ | XRCC6 | P12956 | 2/20 | 0.59 |
| ▸ | XRCC5 | P13010 | 2/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320037 | 0.85 | PRKDC (0.66) | PRKDCXRCC6XRCC5PIK3CBPIK3CD | |
| SCHEMBL7315961 | 0.85 | PRKDC (0.66) | PRKDCXRCC6XRCC5PIK3CBPIK3CD | |
| SCHEMBL7321603 | 0.81 | PRKDC (0.58) | PRKDCXRCC6XRCC5PIK3CBPIK3CD | |
| SCHEMBL7327543 | 0.81 | PRKDC (0.72) | PRKDCXRCC6XRCC5PIK3CBPIK3CD | |
| SCHEMBL28473715 | 0.80 | FAAH (0.60) | PRKDCXRCC6XRCC5PIK3CBHSD17B10 | |
| SCHEMBL7325819 | 0.77 | PRKDC (0.66) | PRKDCXRCC6XRCC5PIK3CBPIK3CD | |
| SCHEMBL7326777 | 0.76 | PRKDC (0.67) | PRKDCXRCC6XRCC5PIK3CBPIK3CD | |
| SCHEMBL7323684 | 0.76 | PRKDC (0.68) | PRKDCXRCC6XRCC5PIK3CBPIK3CD | |
| SCHEMBL31060836 | 0.76 | PRKDC (1.00) | PRKDCHSD17B10 | |
| SCHEMBL31035311 | 0.75 | PRKDC (0.61) | PRKDCHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | claimed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | claimed |
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0525123-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. | UPJOHN CO (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991019707-A2 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |