Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.52 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 7/20 | 0.37 |
| ▸ | MMP7 | P09237 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 7/20 | 0.34 |
| ▸ | MMP12 | P39900 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670933 | 0.84 | MMP1 (0.45) | MMP1MMP2MMP9MMP13MMP7 | |
| SCHEMBL7511113 | 0.84 | MMP1 (0.45) | MMP1MMP2MMP9MMP13MMP7 | |
| SCHEMBL4670840 | 0.73 | MMP1 (0.60) | MMP1MMP2MMP9MMP13MMP7 | |
| SCHEMBL6264715 | 0.73 | MMP1 (0.60) | MMP1MMP2MMP9MMP13MMP7 | |
| SCHEMBL6267896 | 0.72 | MMP1 (0.58) | MMP1MMP2MMP9MMP13MMP7 | |
| SCHEMBL4674797 | 0.71 | MMP1 (0.35) | MMP1MMP2MMP9ADAM17MMP13 | |
| SCHEMBL7462742 | 0.70 | MMP1 (0.32) | MMP1 | |
| SCHEMBL4674939 | 0.70 | MMP1 (0.62) | MMP1MMP2MMP9MMP14MMP13 | |
| SCHEMBL7445328 | 0.69 | MMP13 (0.35) | MMP1MMP9ADAM17MMP13MMP7 | |
| SCHEMBL4671736 | 0.69 | MMP13 (0.35) | MMP1MMP9ADAM17MMP13MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376506-B1 | REACTING SULFAMOYL OXAZOLIDONE WITH (1,2,3,4)-TETRAHYDRO-BETA-CARBOLINE TO FORM INHIBITOR; USED TO TREAT ARTHRITIS, OSTEOPOROSIS, PERIODONTAL DISEASE, CARDIOVASCULAR DISEASES, MULTIPLE SCLEROSIS, AND TUMORS | SYNTEX (U.S.A.) LLC | 2002-04-23 | — | — | US | disclosed |