Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861019 | 0.77 | POLB (0.37) | POLBKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL7242999 | 0.76 | GAA (0.36) | POLBKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL14895480 | 0.75 | SMN1; SMN2 (0.52) | KDM4EGAASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL8903867 | 0.73 | POLB (0.47) | POLBKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL28504265 | 0.72 | POLB (0.48) | POLBKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL8904269 | 0.69 | POLB (0.44) | POLBKDM4EGAASMN1; SMN2ATM | |
| SCHEMBL10856055 | 0.68 | POLB (0.50) | POLBKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL9786463 | 0.67 | GAA (0.57) | POLBKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL19850673 | 0.67 | GAA (0.57) | POLBKDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL19850670 | 0.67 | GAA (0.41) | POLBKDM4ELMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140272065-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-09-18 | — | — | US | disclosed |
| EP-2770849-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2014-09-03 | — | — | EP | disclosed |
| WO-2013060815-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2013-05-02 | — | — | WO | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | disclosed |