Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242999 | 0.79 | GAA (0.36) | POLBSMN1; SMN2GAANPSR1ATM | |
| SCHEMBL7326403 | 0.77 | POLB (0.41) | POLBSMN1; SMN2GAAATMHTT | |
| SCHEMBL14895480 | 0.69 | SMN1; SMN2 (0.52) | SMN1; SMN2GAANPSR1HTTALDH1A1 | |
| SCHEMBL8903867 | 0.68 | POLB (0.47) | POLBSMN1; SMN2GAAHSD17B10ATM | |
| SCHEMBL28504265 | 0.66 | POLB (0.48) | POLBSMN1; SMN2GAAHSD17B10ATM | |
| SCHEMBL831210 | 0.66 | ADORA2B (0.49) | POLBSMN1; SMN2GAANPSR1HSD17B10 | |
| SCHEMBL3710229 | 0.64 | ADORA2B (0.39) | GAANPSR1HSD17B10NPC1HTT | |
| SCHEMBL8904269 | 0.64 | POLB (0.44) | POLBSMN1; SMN2GAAHSD17B10ATM | |
| SCHEMBL7399965 | 0.64 | MAPK1 (0.33) | POLBSMN1; SMN2GAANPSR1NPC1 | |
| SCHEMBL7399962 | 0.64 | MAPK1 (0.33) | POLBSMN1; SMN2GAANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641330-B1 | GABA AND L-GLUTAMIC ACID ANALOGS FOR ANTISEIZURE TREATMENT | UNIV NORTHWESTERN (US) | 2001-10-17 | — | — | EP | disclosed |