Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 19/20 | 0.74 |
| ▸ | MMP1 | P03956 | 17/20 | 0.74 |
| ▸ | MMP13 | P45452 | 15/20 | 0.74 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321971 | 0.89 | ADAM17 (0.70) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL7327430 | 0.88 | ADAM17 (0.69) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL7320672 | 0.88 | MMP1 (0.69) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL7320937 | 0.86 | ADAM17 (0.67) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL7317562 | 0.86 | ADAM17 (0.66) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL7323792 | 0.86 | ADAM17 (0.66) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL6237887 | 0.85 | ADAM17 (1.00) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL6382134 | 0.85 | ADAM17 (1.00) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL7325506 | 0.85 | ADAM17 (0.65) | ADAM17MMP1MMP13MMP9MMP3 | |
| SCHEMBL7318057 | 0.85 | MMP13 (0.60) | ADAM17MMP1MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387901-B1 | ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | PFIZER INC | 2002-05-14 | — | — | US | disclosed |