Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.64 |
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.55 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | UQCRB | P14927 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762452 | 0.88 | PGR (0.74) | PGRIL1RNKEAP1ERAP1ACLY | |
| SCHEMBL28930344 | 0.88 | IL1RN (0.64) | PGRIL1RNKEAP1ERAP1ALDH1A1 | |
| SCHEMBL7171852 | 0.84 | GAA (0.58) | PGRIL1RNKEAP1ERAP1ALDH1A1 | |
| SCHEMBL29562342 | 0.83 | PGR (0.72) | PGRIL1RNKEAP1ERAP1ALDH1A1 | |
| SCHEMBL6275068 | 0.81 | CYP3A4 (0.62) | PGRACLYCYP3A4CYP2D6PSEN1 | |
| SCHEMBL7808166 | 0.80 | MEN1 (0.64) | PGRMEN1KMT2ACYP3A4AVPR2 | |
| SCHEMBL29561644 | 0.79 | HSD17B2 (0.65) | PGRALDH1A1PKMMEN1KMT2A | |
| SCHEMBL3756876 | 0.78 | PGR (1.00) | PGRIL1RNKEAP1ERAP1ALDH1A1 | |
| SCHEMBL16719342 | 0.78 | IL1RN (0.66) | PGRIL1RNKEAP1ERAP1ALDH1A1 | |
| SCHEMBL930801 | 0.75 | UQCRB (0.80) | IL1RNKEAP1ERAP1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |