Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326585 | 0.90 | REN (0.46) | REN | |
| SCHEMBL7326476 | 0.86 | REN (0.52) | REN | |
| SCHEMBL7329651 | 0.85 | REN (0.46) | REN | |
| SCHEMBL7332692 | 0.83 | REN (0.46) | REN | |
| SCHEMBL7327148 | 0.82 | REN (0.47) | REN | |
| SCHEMBL7326488 | 0.78 | REN (0.43) | REN | |
| SCHEMBL7363370 | 0.75 | REN (0.40) | REN | |
| SCHEMBL7324174 | 0.74 | REN (0.64) | REN | |
| SCHEMBL7329648 | 0.73 | REN (0.59) | REN | |
| SCHEMBL7332688 | 0.71 | REN (0.57) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | claimed |
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |