SCHEMBL7329651

SCHEMBL7329651

CC(C)C(O)CC(O)[C@H](CC1CCCCC1)NC(=O)[C@@](N)(Cc1c[nH]cn1)C(=O)C(CC(=O)N1CCOCC1)Cc1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7326585 0.95 REN (0.46) REN
SCHEMBL7332692 0.94 REN (0.46) REN
SCHEMBL7327148 0.94 REN (0.47) REN
SCHEMBL7326488 0.90 REN (0.43) REN
SCHEMBL7329648 0.87 REN (0.59) REN
SCHEMBL7363370 0.86 REN (0.40) REN
SCHEMBL7331453 0.85 REN (0.51) REN
SCHEMBL7326480 0.85 REN (0.40) REN
SCHEMBL9554990 0.82 REN (0.57) REN
SCHEMBL9554999 0.82 REN (0.57) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0396065-A1 Novel amino acid derivatives possessing renin-inhibitory activities Japan Tobacco Inc. (JP) 1990-11-07 EP claimed