Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | PGC | P20142 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354453 | 0.89 | PSEN1 (0.51) | REN | |
| SCHEMBL9354447 | 0.89 | PSEN1 (0.51) | REN | |
| SCHEMBL7329529 | 0.89 | REN (0.50) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7335538 | 0.88 | REN (0.52) | RENCTSDCTSE | |
| SCHEMBL7437602 | 0.82 | REN (0.75) | REN | |
| SCHEMBL7394498 | 0.81 | REN (0.46) | REN | |
| SCHEMBL7360539 | 0.81 | REN (0.46) | REN | |
| SCHEMBL9222943 | 0.81 | REN (0.39) | REN | |
| SCHEMBL7325616 | 0.80 | REN (0.68) | REN | |
| SCHEMBL10510052 | 0.80 | REN (0.42) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |