SCHEMBL732656

SCHEMBL732656

O=C1/C(=C2\Cc3ccccc3C2=O)Cc2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.73
CES1 P23141 2/20 0.67
BCHE P06276 1/20 0.67
ACHE P22303 1/20 0.61
ALDH1A1 P00352 4/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 1/20 0.55
MIF P14174 3/20 0.52
MAOB P27338 1/20 0.52
KDM4E B2RXH2 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TDP2 O95551 1/20 0.48
CASP3 P42574 1/20 0.48
CASP7 P55210 1/20 0.48
CASP9 P55211 1/20 0.48
CASP6 P55212 1/20 0.48
CASP8 Q14790 1/20 0.48
MAP3K14 Q99558 1/20 0.48
CYP19A1 P11511 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102377 0.88 CES1 (0.63) MAOACES1BCHEACHEALDH1A1
SCHEMBL7943906 0.87 ACHE (0.64) MAOACES1BCHEACHEALDH1A1
Anthrone SCHEMBL18143 0.84 MAOA (1.00) MAOACES1BCHEACHEALDH1A1
Anthrone SCHEMBL1527782 0.84 MAOA (1.00) MAOACES1BCHEACHEALDH1A1
Anthrone SCHEMBL29448801 0.84 MAOA (1.00) MAOACES1BCHEACHEALDH1A1
SCHEMBL2319027 0.84 MAOA (0.90) MAOACES1BCHEACHEALDH1A1
Anthrone SCHEMBL29357010 0.84 MAOA (1.00) MAOACES1BCHEACHEALDH1A1
SCHEMBL8160719 0.83 ACHE (0.70) MAOACES1BCHEACHEALDH1A1
Anthraquinone SCHEMBL22026730 0.82 MAOA (0.95) MAOACES1BCHEACHEALDH1A1
Anthrone SCHEMBL22574797 0.82 MAOA (0.95) MAOACES1BCHEACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180017679-A1 DETECTOR FOR AN OPTICAL DETECTION OF AT LEAST ONE OBJECT TRINAMIX GMBH (DE) 2018-01-18 US disclosed
US-8137990-B2 Compositions for chemiluminescent detection of hydrogen peroxide LUMIGEN, INC. (US) 2012-03-20 US disclosed
US-7777847-B2 Liquid crystal display and manufacturing method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-17 US disclosed
US-20100055800-A1 Compositions for Chemiluminescent Detection of Hydrogen Peroxide LUMIGEN, INC. (US) 2010-03-04 US disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 US disclosed