Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 3/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732656 | 0.88 | MAOA (0.73) | CES1MAOAACHEBCHEMAOB | |
| SCHEMBL11671192 | 0.81 | CES1 (0.59) | CES1MAOASRD5A1TDP1L3MBTL1 | |
| SCHEMBL11671185 | 0.81 | CES1 (0.59) | CES1MAOASRD5A1TDP1L3MBTL1 | |
| SCHEMBL8009481 | 0.81 | CES1 (0.59) | CES1MAOASRD5A1TDP1L3MBTL1 | |
| SCHEMBL2903577 | 0.80 | CES1 (0.52) | CES1MAOAACHEBCHESRD5A1 | |
| SCHEMBL29408351 | 0.79 | CES1 (0.90) | CES1MAOABCHETDP1L3MBTL1 | |
| SCHEMBL29437756 | 0.79 | CES1 (0.90) | CES1MAOABCHETDP1L3MBTL1 | |
| SCHEMBL44496 | 0.79 | CES1 (0.90) | CES1MAOABCHETDP1L3MBTL1 | |
| SCHEMBL13712393 | 0.79 | CES1 (1.00) | CES1MAOABCHETDP1L3MBTL1 | |
| SCHEMBL9781046 | 0.78 | MAOA (0.59) | CES1MAOAACHEBCHESRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986530-A1 | INDANE COMPOUNDS AND THEIR PHARMACEUTICAL USE | Venantius Limited (IE) | 2000-03-22 | — | — | EP | claimed |
| WO-1998055439-A1 | INDANE COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LIMITED (IE) | 1998-12-10 | — | — | WO | claimed |
| EP-2221290-B1 | PROCESS FOR PRODUCTION OF ALKOXYINDANONE DERIVATIVES | DNP FINE CHEMICALS UTSUNOMIYA CO LTD (JP) | 2015-01-14 | — | — | EP | disclosed |
| US-8163962-B2 | Method for producing alkoxyindanone derivative | DNP FINE CHEMICALS FUKUSHIMA CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20100261935-A1 | METHOD FOR PRODUCING ALKOXYINDANONE DERIVATIVE | DNP FINE CHEMICALS FUKUSHIMA CO., LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| EP-2221290-A1 | PROCESS FOR PRODUCTION OF ALKOXYINDANONE DERIVATIVES | DNP Fine Chemicals Fukushima Co., Ltd. (JP) | 2010-08-25 | — | — | EP | disclosed |
| EP-0865419-B1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LTD (IE) | 2003-08-06 | — | — | EP | disclosed |
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | disclosed |
| EP-0865419-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | Venantius Limited (IE) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020802-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261935-A1 | METHOD FOR PRODUCING ALKOXYINDANONE DERIVATIVE | ALKBH3, HSD17B12, ALKBH1 | CES1 1116/4885MAOA 1695/4885ACHE 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.