Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.55 |
| ▸ | FABP2 | P12104 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112764 | 0.86 | AKR1C3 (0.59) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL1002973 | 0.83 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL1533399 | 0.83 | AKR1C3 (0.67) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL1932880 | 0.83 | MME (0.41) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL14798202 | 0.81 | MT-CO2 (0.47) | PTGS2PTGS1CYP2C19MAPTHPGD | |
| Acetic Acid SCHEMBL21808210 | 0.81 | PTGS1 (0.47) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL28605589 | 0.80 | PPARG (0.36) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL14465122 | 0.80 | AKR1C3 (0.68) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL31240211 | 0.80 | AKR1C3 (0.68) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 | |
| SCHEMBL287468 | 0.80 | ALDH1A1 (0.63) | AKR1C3AKR1C2PTGS2PTGS1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138335-B2 | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029631-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | GPR17, CYSLTR1, KIT | AKR1C3 774/4885AKR1C2 1407/4885PTGS2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.