Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818014 | 0.90 | SLC6A3 (0.36) | SLC6A4SLC6A3 | |
| SCHEMBL4275497 | 0.85 | HRH3 (0.37) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27827097 | 0.85 | HRH3 (0.37) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27825382 | 0.85 | HRH3 (0.37) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4268661 | 0.85 | HRH3 (0.37) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4281234 | 0.85 | HRH3 (0.37) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL29106969 | 0.85 | HRH3 (0.37) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27715719 | 0.83 | SMN1; SMN2 (0.36) | LMNAALDH1A1HSD17B10SLC6A4SLC6A3 | |
| SCHEMBL4276675 | 0.82 | FDPS (0.36) | LMNATSHR | |
| SCHEMBL4639527 | 0.82 | LMNA (0.36) | LMNAALDH1A1HSD17B10SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |