Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955991 | 1.00 | ACHE (0.51) | ACHETSHRSLC18A2MEN1KMT2A | |
| SCHEMBL6961582 | 0.84 | ACHE (0.51) | ACHETSHRSLC18A2MEN1KMT2A | |
| SCHEMBL6957907 | 0.77 | FUCA1 (0.47) | ACHEMEN1KMT2ASIGMAR1MC4R | |
| SCHEMBL4737149 | 0.77 | FUCA1 (0.47) | ACHEMEN1KMT2ASIGMAR1MC4R | |
| SCHEMBL6947115 | 0.74 | ACHE (0.72) | ACHETSHRMEN1KMT2ASIGMAR1 | |
| SCHEMBL23750981 | 0.71 | ACHE (0.59) | ACHETSHRFAAHKDM4EMAPT | |
| SCHEMBL12123080 | 0.70 | ACHE (0.67) | ACHEFAAHMC4RKDM4EMAPT | |
| SCHEMBL6798169 | 0.70 | ACHE (0.54) | ACHETSHRMEN1KMT2ATMEM97 | |
| SCHEMBL4769588 | 0.69 | FAAH (0.51) | ACHETSHRMEN1KMT2ASIGMAR1 | |
| SCHEMBL8228440 | 0.69 | FAAH (0.51) | ACHETSHRMEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550550-A1 | 3,9-DIAZABICYCLO (3.3.1) NONAN-7-YL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Beecham Group p.l.c. (GB) | 1993-07-14 | — | — | EP | claimed |
| WO-1992005174-A1 | 3,9-DIAZABICYCLO (3.3.1) NONAN-7-YL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1992-04-02 | — | — | WO | claimed |