Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381682 | 0.74 | — | — | |
| SCHEMBL27216297 | 0.67 | CYP3A4 (0.37) | ALDH1A1LMNAHTTEPHX2HCAR2 | |
| SCHEMBL16887582 | 0.64 | ALDH1A1 (0.39) | ALDH1A1LMNAHTTHCAR2ATM | |
| SCHEMBL16887600 | 0.63 | ALDH1A1 (0.38) | ALDH1A1LMNAHCAR2ATM | |
| SCHEMBL6311678 | 0.63 | ALDH1A1 (0.33) | ALDH1A1LMNAATM | |
| SCHEMBL27482066 | 0.63 | HCAR2 (0.41) | ALDH1A1LMNAHTTHCAR2 | |
| SCHEMBL6452242 | 0.63 | EPHX2 (0.52) | ALDH1A1LMNAEPHX2ATM | |
| SCHEMBL9017765 | 0.63 | ALDH1A1 (0.52) | ALDH1A1LMNAHCAR2ATM | |
| SCHEMBL15854345 | 0.62 | ALDH1A1 (0.40) | ALDH1A1LMNAEPHX2HCAR2ATM | |
| SCHEMBL12946630 | 0.62 | ALDH1A1 (0.40) | ALDH1A1LMNAEPHX2HCAR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328200-B1 | Five-membered ring systems with bonded azacyclic ring substituents | MERCK SHARP & DOHME (GB) | 1993-12-08 | — | — | EP | disclosed |