Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 3/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376049 | 0.87 | ALDH1A1 (0.41) | ADAM17MMP1MMP3MMP9GAA | |
| SCHEMBL7373736 | 0.87 | ALDH1A1 (0.41) | ADAM17MMP1MMP3MMP9GAA | |
| SCHEMBL7373729 | 0.87 | ALDH1A1 (0.41) | ADAM17MMP1MMP3MMP9GAA | |
| SCHEMBL7324927 | 0.82 | ANPEP (0.49) | BIRC2TAS1R3TAS1R1ANPEP | |
| SCHEMBL7316826 | 0.82 | ANPEP (0.49) | BIRC2TAS1R3TAS1R1ANPEP | |
| SCHEMBL9492277 | 0.82 | ANPEP (0.49) | BIRC2TAS1R3TAS1R1ANPEP | |
| SCHEMBL9502030 | 0.76 | ALDH1A1 (0.42) | FOLH1 | |
| SCHEMBL9502037 | 0.76 | ALDH1A1 (0.42) | FOLH1 | |
| SCHEMBL7375640 | 0.76 | PPID (0.39) | ADAM17MMP1MMP3MMP9TAS1R3 | |
| SCHEMBL10421717 | 0.75 | TAS1R3 (0.50) | BIRC2TAS1R3TAS1R1POLBANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527764-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |