Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | GRN | P28799 | 2/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502030 | 1.00 | ALDH1A1 (0.42) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL7376049 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL7373736 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL7373729 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL9502827 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL9502831 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL9505358 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL9505878 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL7314091 | 0.78 | CTSK (0.46) | MME | |
| SCHEMBL7316369 | 0.78 | CTSK (0.46) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320118-B1 | PEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| US-4935404-A | ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1990-06-19 | — | — | US | disclosed |
| EP-0320118-A2 | Peptides with collagenase inhibiting activity | BEECHAM GROUP PLC (GB) | 1989-06-14 | — | — | EP | disclosed |