Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346459 | 0.92 | MMP1 (0.56) | MMP1MMP2MMP9MMP12PLA2G7 | |
| SCHEMBL27816663 | 0.90 | SMN1; SMN2 (0.53) | MMP1MMP2MMP9MMP12PLA2G7 | |
| SCHEMBL8207067 | 0.84 | MAPT (0.56) | MMP1MMP2MMP9MMP12HPGD | |
| SCHEMBL27553236 | 0.84 | MMP1 (0.49) | MMP1MMP2MMP9MMP12PLA2G7 | |
| SCHEMBL30481362 | 0.84 | MMP1 (0.49) | MMP1MMP2MMP9MMP12KMT2A | |
| SCHEMBL30291063 | 0.82 | MMP1 (0.54) | MMP1MMP2MMP9MMP12PLA2G7 | |
| SCHEMBL29276385 | 0.82 | MMP1 (0.57) | MMP1MMP2MMP9MMP12PLA2G7 | |
| SCHEMBL28660859 | 0.80 | MMP1 (0.49) | MMP1MMP2MMP9MMP12HPGD | |
| SCHEMBL1036006 | 0.79 | — | — | |
| SCHEMBL28667021 | 0.79 | SRPK1 (0.51) | MMP1MMP2MMP9MMP12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113725370-B | TiO in solar cell2Passivation method for electron transport layer | 西安石油大学 | 2024-07-16 | — | — | CN | claimed |
| US-20220409602-A1 | DOPAMINE D3 RECEPTOR LIGANDS FOR TREATMENT OF DYSKINESIA | TEXAS BIOMEDICAL RESEARCH INSTITUTE (US) | 2022-12-29 | — | — | US | claimed |
| CN-105669506-A | Synthetic method of 2-thiophenylbenzoic acid | 温州大学 | 2016-06-15 | — | — | CN | claimed |
| CN-101525333-B | Synthesis method of metixene hydrochloride | UNIV EAST CHINA NORMAL | 2011-04-27 | — | — | CN | claimed |
| CN-101525333-A | Synthesis method of metixene hydrochloride | UNIV EAST CHINA NORMAL | 2009-09-09 | — | — | CN | claimed |
| US-20050130207-A1 | Small organometallic probes | HAINFELD JAMES F (US) | 2005-06-16 | — | — | US | claimed |
| US-6369206-B1 | OF THE FORMULA (M)N(SR)M WHERE M IS GOLD, SILVER, PLATINUM, PALLADIUM, OR THALLIUM, AND (SR)M IS ORGANOTHIOL MOIETIES; BIOCONJUGATES | NANOPROBES, INC | 2002-04-09 | — | — | US | claimed |
| CN-1036590-C | Process for preparing mercaptoacetylamide derivatives | MERRELL DOW PHARMA (US) | 1997-12-03 | — | — | CN | claimed |
| CN-1061971-A | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and angiotensin converting enzyme | MERRELL DOW PHARMA (US) | 1992-06-17 | — | — | CN | claimed |
| JP-4282382-A | — | — | None | — | — | JP | disclosed |
| CN-114839180-B | Preparation method of spray type bi-component composite Raman substrate | 电子科技大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-115947690-A | Preparation method of indazole molecular building block and application of building block in drug synthesis | 安徽医科大学 | 2023-04-11 | — | — | CN | disclosed |
| US-20220409602-A1 | DOPAMINE D3 RECEPTOR LIGANDS FOR TREATMENT OF DYSKINESIA | TEXAS BIOMEDICAL RESEARCH INSTITUTE (US) | 2022-12-29 | — | — | US | disclosed |
| CN-105669506-A | Synthetic method of 2-thiophenylbenzoic acid | 温州大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-1054590-A | The benzoic acid herbicides that 6-aryl-2-replaces | FMC CORP (US) | 1991-09-18 | — | — | CN | disclosed |
| CN-1034721-A | New tricyclic lactam that contains sulfydryl and the method for on pharmacology, using thereof | MERRELL DOW PHARMA (US) | 1989-08-16 | — | — | CN | disclosed |
| EP-0105224-B1 | ANDROSTENES AND PROCESS FOR THEIR PREPARATION | E.R. Squibb & Sons, Inc. (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4446071-A | Intermediates useful in the preparation of 17,17-bis(substituted thio) androstenes | E. R. SQUIBB & SONS, INC. (US) | 1984-05-01 | — | — | US | disclosed |
| EP-0105224-A2 | Androstenes and process for their preparation | E.R. Squibb & Sons, Inc. (US) | 1984-04-11 | — | — | EP | disclosed |
| US-4435326-A | Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes | E. R. SQUIBB & SONS, INC. (US) | 1984-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220409602-A1 | DOPAMINE D3 RECEPTOR LIGANDS FOR TREATMENT OF DYSKINESIA | DRD3, PARK7, DRD2 | MMP1 4448/4885MMP2 3646/4885MMP9 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.