SCHEMBL7327638

SCHEMBL7327638

CN1[C@@H]2CCC[C@@]1(CCO)CC2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14755359 0.79
SCHEMBL2124580 0.76
Trimethylammonium SCHEMBL30983101 0.72 TSHR (0.32)
SCHEMBL6576076 0.71
SCHEMBL6576075 0.71
SCHEMBL3979443 0.68 HRH3 (0.38)
Bromide SCHEMBL6890863 0.67 KDM4E (0.37)
SCHEMBL4541902 0.66 ALDH1A1 (0.31)
SCHEMBL6944862 0.66 ALDH1A1 (0.31)
SCHEMBL17274595 0.66 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0629190-A1 COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1994-12-21 EP disclosed
WO-1993015052-A1 COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1993-08-05 WO disclosed