Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944862 | 1.00 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL17274595 | 1.00 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7301084 | 0.98 | — | — | |
| SCHEMBL6729329 | 0.95 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL6726321 | 0.95 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL27905008 | 0.89 | — | — | |
| Cycloheptanone SCHEMBL14739731 | 0.84 | TRIM24 (0.35) | ALDH1A1 | |
| SCHEMBL11846859 | 0.72 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL5731681 | 0.70 | — | — | |
| SCHEMBL7305562 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128315-B | Compound, preparation method and application thereof, and glycosidase inhibitor | 中国科学院化学研究所 | 2021-08-20 | — | — | CN | disclosed |
| EP-3253766-B1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | UNIV WASHINGTON (US) | 2019-09-04 | — | — | EP | disclosed |
| US-10399994-B2 | Compounds and methods for preventing or treating sensory hair cell death | UNIVERSITY OF WASHINGTON (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180022756-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | FRED HUTCHINSON CANCER CENTER | 2018-01-25 | — | — | US | disclosed |
| US-20170280643-A1 | Method of Improving the Growth and Production Output of Plants of the Family Solanaceae | ANKNER CHARLES E (US) | 2017-10-05 | — | — | US | disclosed |
| US-9493482-B2 | Compounds and methods for preventing or treating sensory hair cell death | UNIVERSITY OF WASHINGTON (US) | 2016-11-15 | — | — | US | disclosed |
| WO-2016127123-A2 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | UNIVERSITY OF WASHINGTON (US) | 2016-08-11 | — | — | WO | disclosed |
| US-20160229869-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | FRED HUTCHINSON CANCER CENTER | 2016-08-11 | — | — | US | disclosed |
| EP-1493744-B1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX INC (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20070244149-A1 | Tropane analogs and methods for inhibition of monoamine transport | ORGANIX, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-6670375-B2 | Particularly, 8-aza-, 8-carbo- and 8-oxo- tropanes having 6-or 7-substituents; preferred are the dopamine transporter, the serotonin transporter and the norepinephrine transporter. | ORGANIX, INC. | 2003-12-30 | — | — | US | disclosed |
| US-20030105125-A1 | Tropane analogs and methods for inhibition of monoamine transport | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2003-06-05 | — | — | US | disclosed |
| US-20030069269-A1 | Tropane analogs and methods for inhibition of monoamine | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-10 | — | — | US | disclosed |
| US-6417221-B1 | SEROTONIN REUPTAKE INHIBITORS OR ANTISEROTONIN AGENTS | ORGANIX, INC. | 2002-07-09 | — | — | US | disclosed |
| US-6353105-B1 | INHIBITORS OF 5-HYDROXY-TRYPTAMINE REUPTAKE OF A MONOAMINE TRANSPORTER; ANALOGS OF COCAINE; | ORGANIX, INC. | 2002-03-05 | — | — | US | disclosed |
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2002-01-24 | — | — | US | disclosed |
| EP-0996619-A1 | TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT | ORGANIX, INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5948933-A | THERAPY FOR DRUG ABRUSE | ORGANIX, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1999002526-A1 | TROPANE ANALOGS AND METHODS FOR INHIBITION OF MONOAMINE TRANSPORT | ORGANIX, INC. (US) | 1999-01-21 | — | — | WO | disclosed |
| US-4197237-A | Antibodies to nitrogen derivatives of benzoyl ecgonine antigenic conjugates thereof | SYVA COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069269-A1 | Tropane analogs and methods for inhibition of monoamine | SLC6A2, SLC6A4, SLC18A2 | ALDH1A1 690/4885L3MBTL1 3697/4885 |
| US-20160229869-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | CASP3, AIFM1, ATP6V1B1 | ALDH1A1 663/4885L3MBTL1 991/4885 |
| US-10399994-B2 | Compounds and methods for preventing or treating sensory hair cell death | CASP3, AIFM1, ATP6V1B1 | ALDH1A1 663/4885L3MBTL1 991/4885 |
| US-20030105125-A1 | Tropane analogs and methods for inhibition of monoamine transport | SLC6A2, SLC6A4, SLC6A3 | ALDH1A1 391/4885L3MBTL1 3613/4885 |
| US-20020010207-A1 | Tropane analogs and methods for inhibition of monoamine transport | SLC6A2, SLC6A4, SLC6A3 | ALDH1A1 614/4885L3MBTL1 3481/4885 |
| US-20070244149-A1 | Tropane analogs and methods for inhibition of monoamine transport | SLC6A2, SLC6A4, SLC6A3 | ALDH1A1 391/4885L3MBTL1 3613/4885 |
| US-20180022756-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | CASP3, AIFM1, ATP6V1B1 | ALDH1A1 663/4885L3MBTL1 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.