Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335918 | 0.91 | STAT3 (0.40) | KMT2ASMN1; SMN2LMNATSHRPKM | |
| SCHEMBL7325433 | 0.83 | PSMD10 (0.43) | KMT2ASMN1; SMN2LMNATSHRFFAR4 | |
| SCHEMBL7331494 | 0.80 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL13215874 | 0.75 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL7327875 | 0.74 | KMT2A (0.39) | KMT2ASMN1; SMN2LMNATSHRFFAR4 | |
| SCHEMBL7327731 | 0.74 | CYP4A11 (0.43) | KMT2ASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL9868368 | 0.74 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL19211610 | 0.73 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL14778349 | 0.71 | ALDH1A1 (0.44) | KMT2ATSHRALDH1A1 | |
| SCHEMBL14779609 | 0.71 | ALDH1A1 (0.44) | KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4924010-A | GASTROINTESTINAL DISORDERS | RORER PHARMACEUTICAL CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| US-4859683-A | Certain benzoxepins and their pharmaceutical compositions and methods | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| US-4857517-A | Quinuclidyl benzoxepins as 5-HT3 antagonists | RORER PHARMACEUTICAL CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |