Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189733 | 0.89 | TDP1 (0.34) | TDP1POLBNPSR1MAPTATM | |
| SCHEMBL7325648 | 0.86 | AAK1 (0.37) | MMP13AAK1TDP1POLBNPSR1 | |
| SCHEMBL9847303 | 0.84 | SIRT2 (0.31) | — | |
| SCHEMBL12199030 | 0.82 | MAPK1 (0.33) | TACR1ALDH1A1 | |
| SCHEMBL14324686 | 0.82 | MAPK1 (0.33) | TACR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8183614 | 0.81 | ALDH1A1 (0.33) | MAPTTACR1ALDH1A1 | |
| SCHEMBL3341580 | 0.81 | ADORA1 (0.37) | MMP13TDP1NPSR1MAPTATM | |
| SCHEMBL7328213 | 0.80 | ABCB1 (0.47) | MAPTRECQLALDH1A1 | |
| SCHEMBL6833631 | 0.79 | TDP1 (0.33) | TDP1POLBNPSR1MAPTATM | |
| SCHEMBL4891567 | 0.79 | TDP1 (0.33) | TDP1POLBNPSR1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |