Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7328084 | 0.83 | RAB9A (0.46) | RAB9ANPC1MAOBDRD2DRD3 | |
| Oxalic Acid SCHEMBL7318478 | 0.83 | KDM4E (0.44) | KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7328430 | 0.76 | MEN1 (0.47) | RAB9ANPC1MAOBDRD2DRD3 | |
| SCHEMBL7325329 | 0.74 | MAPK1 (0.54) | RAB9AMAOBDRD2DRD3MEN1 | |
| Hydrochloric Acid SCHEMBL7326586 | 0.74 | MAPK1 (0.53) | RAB9AMAOBDRD2DRD3MEN1 | |
| Hydrochloric Acid SCHEMBL7326410 | 0.73 | MAPK1 (0.52) | MAOBDRD2DRD3MEN1KMT2A | |
| Oxalic Acid SCHEMBL7321680 | 0.72 | FAAH (0.49) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL4287375 | 0.69 | RAB9A (0.50) | RAB9ANPC1MAOBDRD2DRD3 | |
| SCHEMBL12735772 | 0.69 | MAOB (0.55) | RAB9ANPC1MAOBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7327265 | 0.69 | MAOB (0.46) | RAB9ANPC1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |