Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328337 | 0.82 | GPR35 (0.62) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL1503796 | 0.82 | RAB9A (0.66) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL1504061 | 0.81 | RAB9A (0.61) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL7573311 | 0.80 | RAB9A (0.68) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL10885626 | 0.79 | RAB9A (0.69) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| Fluoride SCHEMBL10885630 | 0.77 | RAB9A (0.68) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL1091849 | 0.77 | RAB9A (0.68) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL11486413 | 0.77 | HTT (0.61) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL14254814 | 0.77 | ALDH1A1 (0.64) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL12609252 | 0.77 | RAB9A (0.62) | RAB9ACYP1A2CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |