Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328585 | 0.99 | DRD2 (0.41) | GRIN2BGRIN1DRD2DRD3DRD1 | |
| SCHEMBL7329471 | 0.97 | GRIN2B (0.40) | GRIN2BGRIN1DRD2DRD3DRD1 | |
| SCHEMBL7325663 | 0.93 | DRD2 (0.42) | DRD2DRD3DRD1 | |
| SCHEMBL7330395 | 0.88 | DRD2 (0.47) | DRD2DRD3DRD1 | |
| SCHEMBL7328110 | 0.87 | DRD2 (0.48) | DRD2DRD3DRD1 | |
| SCHEMBL7329005 | 0.86 | GRIN2B (0.55) | GRIN2BGRIN1DRD2DRD3DRD1 | |
| SCHEMBL7332957 | 0.86 | HTR1A (0.40) | DRD2DRD3DRD1 | |
| SCHEMBL7327800 | 0.85 | GRIN2B (0.54) | GRIN2BGRIN1DRD2DRD3DRD1 | |
| SCHEMBL7329557 | 0.84 | DRD2 (0.47) | DRD2DRD3DRD1 | |
| SCHEMBL7328536 | 0.83 | GRIN2B (0.49) | GRIN2BGRIN1DRD2DRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |