Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.61 |
| ▸ | P4HB | P07237 | 14/20 | 0.56 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280201 | 0.91 | ACHE (0.71) | ACHEP4HBSMAD3OPRM1OPRD1 | |
| SCHEMBL16226328 | 0.84 | ACHE (0.63) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL7440651 | 0.82 | ACHE (0.61) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9720694 | 0.78 | ATM (0.69) | ACHEOPRM1OPRK1 | |
| SCHEMBL16225811 | 0.76 | ACHE (1.00) | ACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL23565685 | 0.76 | ACHE (0.49) | ACHEP4HBSMAD3 | |
| SCHEMBL7324298 | 0.75 | OPRD1 (0.57) | ACHEP4HBALDH1A1OPRM1OPRD1 | |
| SCHEMBL7427630 | 0.74 | CYP2D6 (0.59) | ACHEP4HBOPRM1OPRD1OPRK1 | |
| SCHEMBL16226434 | 0.74 | ACHE (1.00) | ACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL8802768 | 0.73 | ACHE (0.56) | ACHEOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |