Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | P4HB | P07237 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336219 | 0.93 | CYP2D6 (0.67) | CYP2D6CYP19A1MEN1KMT2AACHE | |
| SCHEMBL16225886 | 0.86 | MEN1 (0.79) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL1138318 | 0.86 | MEN1 (0.79) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL1138320 | 0.86 | MEN1 (0.79) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL8182035 | 0.85 | CYP2D6 (0.57) | CYP2D6CYP19A1MEN1KMT2AACHE | |
| SCHEMBL11193886 | 0.83 | CYP2D6 (0.56) | CYP2D6CYP19A1MEN1KMT2AACHE | |
| SCHEMBL8479321 | 0.82 | MEN1 (0.85) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| Acetic Acid SCHEMBL27992925 | 0.82 | OPRD1 (0.65) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL16226147 | 0.82 | MEN1 (0.67) | CYP2D6CYP19A1MEN1KMT2AOPRD1 | |
| SCHEMBL14280201 | 0.81 | ACHE (0.71) | MEN1KMT2AACHEOPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661148-A | ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER | TEIJIN LIMITED (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0514540-B1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-07-17 | — | — | EP | disclosed |
| EP-0283310-B1 | N-BENZHYDRYL-SUBSTITUTED HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0514540-A1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1992-11-25 | — | — | EP | disclosed |
| US-5028610-A | Calcium Channel Blockers | SANKYO COMPANY LIMITED (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0283310-A1 | N-Benzhydryl-substituted heterocyclic derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-09-21 | — | — | EP | disclosed |