Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331035 | 0.86 | MAPT (0.48) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7329545 | 0.82 | TNKS (0.41) | MAPTRAB9AMEN1KMT2AMCL1 | |
| SCHEMBL7327732 | 0.81 | TNKS (0.39) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL7337601 | 0.79 | TNKS (0.43) | TNKSTNKS2PARP1PARP2 | |
| SCHEMBL7337908 | 0.76 | SCN10A (0.38) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL15286811 | 0.74 | TNKS (0.59) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7329217 | 0.72 | TNKS (0.67) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL20401760 | 0.64 | MAPT (0.59) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3179267 | 0.61 | MAPT (0.62) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL25882279 | 0.61 | HSD17B10 (0.50) | MAPTRAB9AALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726900-A1 | 7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS | Aventis Pharma S.A. (FR) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012594-A1 | 7H-IMIDAZO(1,2-a)PYRAZINE-8-ONE NMDA RECEPTOR ANTAGONISTS | RHONE-POULENC RORER S.A. (FR) | 1995-05-11 | — | — | WO | disclosed |