Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 2/20 | 0.66 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.56 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369354 | 0.90 | TCF4 (0.80) | TCF4CTNNB1LMNASMN1; SMN2POLB | |
| SCHEMBL1726857 | 0.85 | LMNA (0.76) | TCF4CTNNB1LMNASMN1; SMN2POLB | |
| SCHEMBL12441805 | 0.82 | TCF4 (0.62) | TCF4CTNNB1LMNASMN1; SMN2POLB | |
| SCHEMBL2941161 | 0.81 | CA12 (0.69) | TCF4CTNNB1LMNASMN1; SMN2POLB | |
| SCHEMBL894613 | 0.81 | POLB (0.82) | POLBPFKFB3ITGA1MEN1KMT2A | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL4057888 | 0.80 | IL1RN (0.65) | TCF4CTNNB1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8285647 | 0.80 | TCF4 (0.64) | TCF4CTNNB1LMNASMN1; SMN2POLB | |
| SCHEMBL16116948 | 0.80 | TCF4 (1.00) | TCF4CTNNB1LMNASMN1; SMN2POLB | |
| SCHEMBL14896438 | 0.80 | TCF4 (0.80) | TCF4CTNNB1LMNASMN1; SMN2POLB | |
| SCHEMBL31253926 | 0.80 | TCF4 (1.00) | TCF4CTNNB1LMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |