Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 2/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369354 | 0.88 | TCF4 (0.80) | TCF4CTNNB1POLBACLYPLAU | |
| SCHEMBL8284562 | 0.84 | HDAC8 (0.70) | GAAHPGDPOLBMAPTPFKFB3 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL4057888 | 0.81 | IL1RN (0.65) | TCF4CTNNB1GAAHPGDPLAU | |
| SCHEMBL5316103 | 0.81 | TSHR (0.60) | HPGDPOLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16116946 | 0.80 | TCF4 (0.74) | TCF4CTNNB1GAAHPGDPOLB | |
| SCHEMBL7328487 | 0.80 | TCF4 (0.66) | TCF4CTNNB1GAAHPGDPOLB | |
| SCHEMBL16116948 | 0.78 | TCF4 (1.00) | TCF4CTNNB1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL31253926 | 0.78 | TCF4 (1.00) | TCF4CTNNB1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL14896438 | 0.78 | TCF4 (0.80) | TCF4CTNNB1GAAHPGDPOLB | |
| SCHEMBL8249331 | 0.77 | KDM4E (0.70) | TCF4CTNNB1GAAHPGDPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061448-A1 | COMPOSITIONS AND METHODS FOR TREATING VASCULAR CONDITIONS | MONASH UNIVERSITY (AU) | 2005-07-07 | — | — | WO | disclosed |