Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686919 | 1.00 | ALDH1A1 (0.61) | ALDH1A1GAAHTTSMN1; SMN2LMNA | |
| SCHEMBL8393267 | 0.94 | HTT (0.65) | ALDH1A1GAAHTTSMN1; SMN2LMNA | |
| SCHEMBL8395610 | 0.88 | HTT (0.62) | ALDH1A1HTTSMN1; SMN2LMNATGM2 | |
| SCHEMBL8392818 | 0.88 | HTT (0.62) | ALDH1A1GAAHTTSMN1; SMN2LMNA | |
| SCHEMBL8392487 | 0.87 | MEN1 (0.62) | ALDH1A1HTTSMN1; SMN2LMNATGM2 | |
| SCHEMBL8395472 | 0.87 | MEN1 (0.62) | ALDH1A1HTTSMN1; SMN2LMNATGM2 | |
| SCHEMBL8396587 | 0.85 | LMNA (0.63) | ALDH1A1GAAHTTSMN1; SMN2LMNA | |
| SCHEMBL30500863 | 0.85 | HTT (0.58) | GAAHTTSMN1; SMN2LMNATGM2 | |
| SCHEMBL594857 | 0.84 | ALDH1A1 (0.67) | ALDH1A1GAAHTTSMN1; SMN2LMNA | |
| SCHEMBL594858 | 0.84 | ALDH1A1 (0.67) | ALDH1A1GAAHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370498-A2 | Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |