Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | NR0B1 | P51843 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16568945 | 0.76 | ALDH1A1 (0.55) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL10209096 | 0.72 | SLC6A2 (0.49) | MEN1KMT2AL3MBTL1LMNATSHR | |
| SCHEMBL7322864 | 0.71 | SMARCA2 (0.46) | MEN1KMT2AMMELMNA | |
| SCHEMBL1652624 | 0.69 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2ANR0B1 | |
| SCHEMBL5631579 | 0.68 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2ANR0B1 | |
| SCHEMBL4449131 | 0.68 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2ANR0B1 | |
| SCHEMBL6361946 | 0.67 | RAB9A (0.58) | NPC1RAB9AMEN1KMT2ANR0B1 | |
| SCHEMBL16321284 | 0.67 | RAB9A (0.58) | NPC1RAB9AMEN1KMT2ANR0B1 | |
| SCHEMBL7929910 | 0.67 | RAB9A (0.58) | NPC1RAB9AMEN1KMT2ANR0B1 | |
| SCHEMBL3494324 | 0.67 | ALDH1A1 (0.50) | NPC1RAB9AMEN1KMT2AMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370498-A2 | Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |