Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16568945 | 0.74 | ALDH1A1 (0.55) | MEN1KMT2ALMNA | |
| SCHEMBL10209096 | 0.73 | SLC6A2 (0.49) | MEN1KMT2ALMNAGAAHDAC1 | |
| Hydrochloric Acid SCHEMBL29928336 | 0.72 | LMNA (0.50) | PRMT3LMNACETPROCK2ROCK1 | |
| SCHEMBL27830970 | 0.72 | OPRM1 (0.47) | SMARCA2SMARCA4SORT1MEN1KMT2A | |
| SCHEMBL7328714 | 0.71 | NPC1 (0.46) | MEN1KMT2ALMNAMME | |
| SCHEMBL15880595 | 0.71 | SMARCA2 (0.61) | SMARCA2SMARCA4SORT1MEN1KMT2A | |
| SCHEMBL15880685 | 0.70 | SMARCA2 (0.65) | SMARCA2SMARCA4SORT1MEN1KMT2A | |
| SCHEMBL26050255 | 0.70 | SMARCA2 (0.44) | SMARCA2SMARCA4SORT1MEN1KMT2A | |
| SCHEMBL7345225 | 0.69 | PLAU (0.53) | — | |
| SCHEMBL7672757 | 0.69 | SMARCA2 (0.63) | SMARCA2SMARCA4SORT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370498-A2 | Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | claimed |