Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450723 | 0.89 | TRPA1 (0.31) | TSHRTRPA1ALDH1A1 | |
| SCHEMBL15953591 | 0.83 | TDP1 (0.43) | CYP1A2CYP2D6CYP2C19IDO1TDP1 | |
| SCHEMBL8955219 | 0.80 | CA12 (0.35) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9008790 | 0.79 | TDP1 (0.50) | TSHRALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6947245 | 0.78 | ACHE (0.46) | TSHRTRPA1ALDH1A1IDO1CES2 | |
| SCHEMBL8954887 | 0.77 | IDO1 (0.42) | CYP1A2CYP2D6CYP2C19IDO1CA2 | |
| SCHEMBL7349245 | 0.77 | HRH3 (0.44) | CYP1A2CYP2D6CYP2C19IDO1 | |
| SCHEMBL19640126 | 0.77 | TTR (0.37) | TSHRCYP1A2CYP2D6CYP2C19IDO1 | |
| SCHEMBL2938648 | 0.77 | LTA4H (0.39) | TSHRCYP1A2CYP2D6CYP2C19IDO1 | |
| SCHEMBL11249724 | 0.76 | PTGS1 (0.50) | TSHRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014203132-A1 | SUBSTITUTED BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| US-20090023842-A1 | PORPHYRIN AND CONDUCTIVE POLYMER COMPOSITIONS FOR USE IN SOLID-STATE ELECTRONIC DEVICES | PLEXTRONICS, INC. | 2009-01-22 | — | — | US | disclosed |
| US-20090023842-A1 | PORPHYRIN AND CONDUCTIVE POLYMER COMPOSITIONS FOR USE IN SOLID-STATE ELECTRONIC DEVICES | PLEXTRONICS, INC. | 2009-01-22 | — | — | US | disclosed |
| WO-2008144750-A1 | PORPHYRIN AND CONDUCTIVE POLYMER COMPOSITIONS FOR USE IN SOLID-STATE ELECTRONIC DEVICES | PLEXTRONICS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| EP-0434365-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0145263-B1 | LIVING POLYMERS AND PROCESS FOR THEIR PREPARATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4783500-A | ORGANO-SILICON,-TIN, OR -GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4711942-A | FROM ACRYLIC OR MALEIMIDE MONOMER AND ORGANOSILICON,-TIN, OR -GERMANIUM INITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-08 | — | — | US | disclosed |
| US-4681918-A | ACRYLIC-TYPE OR MALEIMIDE MONOMERS; ORGANOSILICON, TIN OR GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0068887-B1 | \"LIVING\" POLYMERS AND PROCESS FOR THEIR PREPARATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4581428-A | Process for preparing \"living\" polymers using tetracoordinate organosilicon, organotin or organogermanium polymerization initiator with bifluoride ion source co-catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0145263-A1 | Living polymers and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4524196-A | Process for preparing \"living\" polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| US-4508880-A | ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |
| US-4417034-A | POLYMERIZING ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANO-SILICON, -TIN, OR-GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4414372-A | ADDITION POLYMERS WITH FUNCTIONAL END GROUPS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0068887-A1 | \"Living\" polymers and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |