Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328848 | 1.00 | FFAR1 (0.42) | FFAR1HPGDS1PR1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11740533 | 0.96 | FFAR1 (0.40) | FFAR1HPGDS1PR1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11745241 | 0.89 | PPARG (0.36) | LTA4H | |
| SCHEMBL11738772 | 0.89 | PSMB1 (0.36) | LTA4H | |
| SCHEMBL11738764 | 0.89 | PSMB1 (0.36) | LTA4H | |
| SCHEMBL11775575 | 0.86 | CTSD (0.36) | MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11776520 | 0.85 | MAOA (0.36) | MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11737896 | 0.85 | MAOA (0.36) | MAOAMAOB | |
| Hydrochloric Acid SCHEMBL11741353 | 0.84 | SLC2A1 (0.41) | HPGDSLC2A1LTA4H | |
| Hydrochloric Acid SCHEMBL11741356 | 0.84 | SLC2A1 (0.41) | HPGDSLC2A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198433-A | Hypotensive | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-30 | — | — | US | disclosed |
| US-5158945-A | Cardiotonic agents, vasodilators, hypotensive agents, anticonvulsants, antiisichemic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0370320-B1 | LACTAMIMIDES IN THE TREATMENT OF DRUG-RESISTANT PROTOZOAL INFECTIONS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-09-30 | — | — | EP | disclosed |
| US-5128337-A | Hypotensive agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-07 | — | — | US | disclosed |
| US-5082837-A | Hypotensive | MERRELL DOW PHARMACEUTICALS (US) | 1992-01-21 | — | — | US | disclosed |
| US-5010072-A | Hypotensive agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4061746-A | Lactamimide inhibitors of gastrointestinal hypersecretion | RICHARDSON-MERRELL INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4055561-A | ANTICOAGULANT | RICHARDSON-MERRELL INC. (US) | 1977-10-25 | — | — | US | disclosed |