Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9296670 | 0.95 | GAA (0.39) | GAAMAPTMEN1KMT2AFPR2 | |
| Trifluoroacetic Acid SCHEMBL7319506 | 0.88 | MAPT (0.40) | GAAMAPTMEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL7330577 | 0.83 | ITGB1 (0.40) | GAAMAPTMEN1KMT2AFPR2 | |
| Trifluoroacetic Acid SCHEMBL7327884 | 0.79 | NPY4R (0.41) | GAAMAPTMEN1KMT2AMMP2 | |
| SCHEMBL7325092 | 0.79 | MMP2 (0.41) | MEN1KMT2AFPR2ATMMMP2 | |
| SCHEMBL7316571 | 0.79 | MMP2 (0.44) | GAAMAPTMEN1KMT2AFPR2 | |
| SCHEMBL7326943 | 0.79 | MMP2 (0.44) | GAAMAPTMEN1KMT2AFPR2 | |
| SCHEMBL7326842 | 0.79 | MMP2 (0.44) | GAAMAPTMEN1KMT2AFPR2 | |
| SCHEMBL7326730 | 0.78 | ITGB3 (0.41) | GAAMAPTFPR2 | |
| SCHEMBL7323827 | 0.75 | ENPEP (0.42) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | claimed |
| WO-1992018117-A1 | ANTI-THROMBOTIC PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-10-29 | — | — | WO | disclosed |