Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648996 | 1.00 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL8648992 | 1.00 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL7269454 | 0.91 | KLK5 (0.61) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL8647459 | 0.91 | KLK5 (0.61) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL8647455 | 0.91 | KLK5 (0.61) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL8547761 | 0.91 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL8547758 | 0.91 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL8547755 | 0.91 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BADORA1MMEL1 | |
| SCHEMBL7267752 | 0.89 | ACE (0.60) | ADORA3ADORA2AADORA2BADORA1CTSL | |
| SCHEMBL7393230 | 0.89 | ACE (0.60) | ADORA3ADORA2AADORA2BADORA1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610743-B1 | Aminomethylene-peptides as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0610743-A1 | Novel aminomethylene-peptides as immunosuppressants | Bayer Corporation (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |