Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329238 | 0.81 | ALDH1A1 (0.40) | PIN1NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27573148 | 0.68 | DAGLA (0.76) | DAGLANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7542370 | 0.66 | BCHE (0.43) | ITGB3ITGA2BPIN1ITGAVNPC1 | |
| SCHEMBL7347037 | 0.65 | ALDH1A1 (0.56) | DAGLAPIN1NPC1ALDH1A1RAB9A | |
| SCHEMBL7347042 | 0.65 | ALDH1A1 (0.56) | DAGLAPIN1NPC1ALDH1A1RAB9A | |
| SCHEMBL6032775 | 0.64 | ITGB3 (0.64) | ITGB3ITGA2BITGAVALDH1A1CHRM2 | |
| SCHEMBL7329235 | 0.64 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3962735 | 0.63 | DAGLA (1.00) | DAGLANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5603960 | 0.62 | ITGB3 (0.61) | ITGB3ITGA2BITGAVALDH1A1CHRM2 | |
| SCHEMBL7622370 | 0.62 | ITGB3 (0.61) | ITGB3ITGA2BITGAVALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |