Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11659282 | 0.97 | GRIN1 (0.54) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Methyl Alcohol SCHEMBL28176117 | 0.95 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL3382980 | 0.95 | GRIN1 (0.46) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL28090077 | 0.87 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Formic Acid SCHEMBL28177121 | 0.87 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Acetamide SCHEMBL4785229 | 0.85 | GRIN1 (0.45) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL812216 | 0.83 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL26079848 | 0.83 | GRIN1 (0.38) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Ammonia Solution, Strong SCHEMBL14695768 | 0.80 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL11657544 | 0.80 | MEN1 (0.47) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119936252-A | Memantine hydrochloride and detection method of related substances thereof | 宁夏医科大学 | 2025-05-06 | — | — | CN | claimed |
| CN-116947644-B | Preparation method of memantine hydrochloride | 山东轩鸿生物医药有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-116046926-B | Detection method of 1-bromo-3, 5-dimethyl adamantane related substances | 合肥久诺医药科技有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-117486929-A | Substituted alkyl germanium compound and modularized synthesis method thereof | 西安交通大学 | 2024-02-02 | — | — | CN | claimed |
| CN-116947644-A | Preparation method of memantine hydrochloride | 山东轩鸿生物医药有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116395671-A | Preparation method of magnetic carbon quantum dot with high relaxation rate | 中国科学院上海微系统与信息技术研究所 | 2023-07-07 | — | — | CN | claimed |
| CN-116285974-A | Preparation method of carbon-based quantum dot with high quantum yield and light stability | 中国科学院上海微系统与信息技术研究所 | 2023-06-23 | — | — | CN | claimed |
| CN-111909041-B | Preparation method of medicine for treating neurological diseases | 山东罗欣药业集团恒欣药业有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-111701600-B | Catalyst for preparing 1-bromo-3, 5-dimethyl adamantane and application thereof | 沧州那瑞化学科技有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-116046926-A | Detection method of 1-bromo-3, 5-dimethyl adamantane related substances | 合肥久诺医药科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| EP-1836157-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-3,5-DIMETHYLADAMANTANE HYDROCHLORIDE | Teva Pharmaceutical Fine Chemicals S.R.L. (IT) | 2007-09-26 | — | — | EP | claimed |
| US-20070078283-A1 | Method of preparing memantine hydrochloride | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY | 2007-04-05 | — | — | US | claimed |
| WO-2006122238-A1 | PROCESS FOR PREPARING MEMANTINE | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-11-16 | — | — | WO | claimed |
| US-20060173215-A1 | Process for the preparation of 1-amino-3,5-dimethyladamantane hydrochloride | TEVA PHARMACEUTICALS USA, INC. | 2006-08-03 | — | — | US | claimed |
| WO-2006076562-A1 | PROCESS FOR THE PREPARATION OF 1-AMINO-3,5-DIMETHYLADAMANTANE HYDROCHLORIDE | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2006-07-20 | — | — | WO | claimed |
| EP-1674446-A1 | A METHOD OF PREPARING MEMANTINE HYDROCHLORIDE | Shanghai Institute of Pharmaceutical Industry (CN) | 2006-06-28 | — | — | EP | claimed |
| CN-1240668-C | Method for preparing memantine hydrochloride | SHANGHAI INST PHARM INDUSTRY (CN) | 2006-02-08 | — | — | CN | claimed |
| CN-1594277-A | Method for preparing memantine hydrochloride | SHANGHAI INST PHARM INDUSTRY (CN) | 2005-03-16 | — | — | CN | claimed |
| US-6797745-B1 | Hot melt inks containing styrene or terpene polymers | XEROX CORPORATION | 2004-09-28 | — | — | US | claimed |
| CN-1400205-A | Preparation method of memantine hydrochloride | GUANGZHOU INST OF CHEMISTRY (CN) | 2003-03-05 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173215-A1 | Process for the preparation of 1-amino-3,5-dimethyladamantane hydrochloride | HTR5A, HNMT, HTR1A | GRIN1 56/4885GRIN2A 42/4885GRIN2D 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.