Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | PGC | P20142 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331112 | 0.92 | CTSD (0.43) | CDYL2CDYLCYP2C19SMN1; SMN2CTSD | |
| SCHEMBL7321670 | 0.83 | PSEN1 (0.43) | CYP2C19SMN1; SMN2BACE1CTSDCTSE | |
| SCHEMBL7330516 | 0.82 | CDYL2 (0.47) | CDYL2CDYLCALCRLBACE1CTSB | |
| SCHEMBL7322717 | 0.81 | PSEN1 (0.51) | CTSDPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7326356 | 0.79 | CTSD (0.39) | CYP2C19SMN1; SMN2CALCRLBACE1CTSD | |
| SCHEMBL7324985 | 0.76 | ANPEP (0.45) | CYP2C19SMN1; SMN2CTSDPSMB5 | |
| SCHEMBL7330442 | 0.76 | ANPEP (0.45) | CYP2C19SMN1; SMN2CTSDPSMB5 | |
| SCHEMBL10378717 | 0.75 | BACE1 (0.58) | CDYL2CDYLCALCRLBACE1CTSD | |
| SCHEMBL7329186 | 0.75 | BACE1 (0.58) | CDYL2CDYLCALCRLBACE1CTSD | |
| SCHEMBL7323521 | 0.75 | CDYL2 (0.41) | CDYL2CDYLCYP2C19CTSDCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |