Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324985 | 1.00 | ANPEP (0.45) | ANPEPKLK5CTSDKMT2AMEN1 | |
| SCHEMBL7331112 | 0.85 | CTSD (0.43) | KLK5CTSDKMT2AMEN1CYP2C19 | |
| SCHEMBL7326474 | 0.82 | TSHR (0.38) | KMT2AMEN1PSMB5 | |
| SCHEMBL7321670 | 0.80 | PSEN1 (0.43) | KLK5CTSDPSMB5CYP2C19SMN1; SMN2 | |
| SCHEMBL7322717 | 0.78 | PSEN1 (0.51) | KLK5CTSDKMT2A | |
| SCHEMBL7330454 | 0.78 | PSEN1 (0.40) | KLK5CTSDKMT2ACYP2C19SMN1; SMN2 | |
| SCHEMBL7326356 | 0.77 | CTSD (0.39) | KLK5CTSDCYP2C19SMN1; SMN2 | |
| SCHEMBL7329194 | 0.76 | CDYL2 (0.43) | CTSDPSMB5CYP2C19SMN1; SMN2 | |
| SCHEMBL7323521 | 0.74 | CDYL2 (0.41) | CTSDKMT2AMEN1PSMB5CYP2C19 | |
| SCHEMBL7328692 | 0.73 | CTSD (0.54) | ANPEPKLK5CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |