Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ACR | P10323 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330746 | 0.86 | FTO (0.48) | SLC6A3FTOTMPRSS15PRSS1PARP10 | |
| SCHEMBL7324828 | 0.85 | FTO (0.47) | SLC6A3FTOTMPRSS15PRSS1PARP10 | |
| SCHEMBL7326063 | 0.85 | SLC6A3 (0.62) | SLC6A3PRSS1PARP10KMT2AACR | |
| SCHEMBL7329213 | 0.83 | ESR1 (0.52) | SLC6A3TMPRSS15PRSS1PARP10KMT2A | |
| SCHEMBL7321924 | 0.82 | SLC6A3 (0.47) | SLC6A3PRSS1PARP10KMT2AACR | |
| SCHEMBL10851091 | 0.81 | FTO (0.52) | SLC6A3FTOTMPRSS15PRSS1PARP10 | |
| Bicarbonate SCHEMBL7333292 | 0.81 | SLC6A3 (0.46) | SLC6A3TMPRSS15PRSS1PARP10KMT2A | |
| SCHEMBL7323721 | 0.79 | TMPRSS15 (0.54) | SLC6A3FTOTMPRSS15PRSS1PARP10 | |
| SCHEMBL7332318 | 0.79 | MAPT (0.58) | FTOPRSS1KMT2AACRHPGD | |
| SCHEMBL7332959 | 0.79 | RAB9A (0.45) | SLC6A3FTOTMPRSS15PRSS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |