Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.51 |
| ▸ | CTSD | P07339 | 9/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329337 | 1.00 | REN (0.51) | RENCTSDBACE1 | |
| SCHEMBL7332534 | 0.94 | CTSD (0.54) | RENCTSDBACE1 | |
| SCHEMBL7325303 | 0.92 | REN (0.49) | RENCTSDBACE1 | |
| SCHEMBL7332555 | 0.89 | CTSD (0.58) | RENCTSDBACE1 | |
| SCHEMBL7331052 | 0.88 | CTSD (0.63) | RENCTSDBACE1 | |
| SCHEMBL7320103 | 0.88 | CTSD (0.59) | RENCTSD | |
| SCHEMBL7329209 | 0.87 | CTSD (0.64) | RENCTSDBACE1 | |
| SCHEMBL7328968 | 0.86 | CTSD (0.54) | RENCTSDBACE1 | |
| SCHEMBL7328082 | 0.85 | CTSD (0.55) | RENCTSDBACE1 | |
| SCHEMBL7328076 | 0.85 | CTSD (0.55) | RENCTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |