Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 13/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330747 | 0.97 | ELANE (0.39) | ELANECMA1CTSKCTSLCTSB | |
| SCHEMBL8510794 | 0.95 | ELANE (0.41) | ELANECMA1CTSKCTSLCTSB | |
| SCHEMBL7966452 | 0.91 | ELANE (0.41) | ELANECMA1CTSKCTSLCTSB | |
| SCHEMBL7860595 | 0.87 | ELANE (0.46) | ELANECMA1CTSKCTSLCTSB | |
| SCHEMBL8428583 | 0.80 | ELANE (0.37) | ELANECMA1MEN1KMT2A | |
| SCHEMBL7860728 | 0.79 | ELANE (0.41) | ELANECMA1MEN1KMT2A | |
| SCHEMBL8430198 | 0.78 | ELANE (0.38) | ELANECMA1MEN1KMT2A | |
| SCHEMBL7881751 | 0.77 | CTSL (0.43) | ELANECMA1CTSKCTSLCTSB | |
| SCHEMBL7964797 | 0.77 | ELANE (0.44) | ELANECMA1 | |
| SCHEMBL8430121 | 0.77 | ELANE (0.61) | ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008196-A | AN ENZYME INHIBITORS OF HUMAN NEUTROPHIL ELASTASE | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0763055-B1 | PERFLUOROALKYL KETONE INHIBITORS OF ELASTASE AND PROCESSES FOR MAKING THE SAME | MERRELL PHARMA INC (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0763055-A1 | PERFLUOROALKYL KETONE INHIBITORS OF ELASTASE AND PROCESSES FOR MAKING THE SAME | MERRELL PHARMACEUTICALS INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033762-A1 | PERFLUOROALKYL KETONE INHIBITORS OF ELASTASE AND PROCESSES FOR MAKING THE SAME | MERRELL PHARMACEUTICALS INC. (US) | 1995-12-14 | — | — | WO | disclosed |