Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226475 | 0.85 | PLA2G2A (0.44) | TDP1AKR1B1PTPN1ALDH1A1MEN1 | |
| SCHEMBL2458016 | 0.83 | GPR84 (0.39) | TDP1NSD2ABL1GAAIDE | |
| SCHEMBL7324226 | 0.81 | APEX1 (0.45) | TDP1NSD2ABL1GAAIDE | |
| SCHEMBL11168354 | 0.80 | APEX1 (0.47) | TDP1NSD2ABL1GAAIDE | |
| SCHEMBL7324274 | 0.76 | PTPN1 (0.39) | LMNATSHRHDAC3HDAC1HDAC2 | |
| SCHEMBL7320019 | 0.72 | F13A1 (0.47) | TDP1LMNATSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL518168 | 0.68 | LMNA (0.92) | TDP1LMNATSHRNFKB1PMP22 | |
| Sebacic Acid SCHEMBL2237815 | 0.65 | TSHR (0.92) | TDP1LMNATSHRNFKB1PMP22 | |
| SCHEMBL6049863 | 0.65 | TSHR (0.92) | TDP1LMNATSHRNFKB1PMP22 | |
| Octanedioate SCHEMBL11076791 | 0.65 | TSHR (0.92) | TDP1LMNATSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | claimed |
| JP-51128932-A | — | — | None | — | — | JP | disclosed |
| US-4525361-A | FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4407757-A | IMMUNOLOGY AGENT, MUSCLE RELAXANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4271083-A | IMMUNO-POTENTIATING ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | disclosed |
| JP-S51128932-A | ORGANIC COMPOUNDS | TAKEDA CHEM IND LTD | 1976-11-10 | — | — | JP | disclosed |