Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 11/20 | 0.51 |
| ▸ | ACHE | P22303 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584061 | 0.93 | ALDH1A1 (0.54) | MAOANPC1RAB9AXDHALDH1A1 | |
| SCHEMBL7965236 | 0.92 | ALDH1A1 (0.57) | MAOANPC1RAB9AXDHALDH1A1 | |
| SCHEMBL8484884 | 0.91 | ALDH1A1 (0.49) | MAOANPC1RAB9AXDHALDH1A1 | |
| SCHEMBL8485841 | 0.84 | MAOA (0.50) | MAOAXDHALDH1A1TP53CYP3A4 | |
| SCHEMBL11030589 | 0.82 | MAOA (0.62) | MAOA | |
| SCHEMBL10486606 | 0.81 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1TP53CYP3A4 | |
| SCHEMBL11029477 | 0.80 | MAOA (0.68) | MAOANPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL10812065 | 0.80 | ALDH1A1 (0.55) | MAOANPC1RAB9AALDH1A1TP53 | |
| SCHEMBL10807772 | 0.80 | ALDH1A1 (0.65) | MAOANPC1RAB9AALDH1A1TP53 | |
| SCHEMBL31060715 | 0.80 | MAOA (0.68) | MAOANPC1RAB9AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741813-A | ADMINISTERING SUBSTITUTED XANTHONES | NATIONAL SCIENCE COUNCIL (TW) | 1998-04-21 | — | — | US | claimed |
| US-5981774-A | PREPARING 3,5-DI(2,3-EPOXYPROPOXY)-1-HYDROXYXANTHONE BY REACTING 1,3,5-TRIMETHOXYXANTHONE WITH HYDROGEN IODIDE IN PHENOL WHEREBY 1,3,5-TRIHYDROXYXANTHONE IS OBTAINED, REACTING PRODUCT WITH EPICHLOROHYDRIN IN POTASSIUM HYDROXIDE | NATIONAL SCIENCE COUNCIL (TW) | 1999-11-09 | — | — | US | disclosed |
| US-5741813-A | ADMINISTERING SUBSTITUTED XANTHONES | NATIONAL SCIENCE COUNCIL (TW) | 1998-04-21 | — | — | US | disclosed |
| US-5495005-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | NATIONAL SCIENCE COUNCIL (TW) | 1996-02-27 | — | — | US | disclosed |