Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 9/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332307 | 0.74 | DCTPP1 (0.49) | IDO1DCTPP1TDO2 | |
| SCHEMBL7339811 | 0.73 | DCTPP1 (0.43) | DCTPP1GRM5PTGS2 | |
| SCHEMBL7339805 | 0.73 | DCTPP1 (0.43) | DCTPP1GRM5PTGS2 | |
| SCHEMBL7338080 | 0.72 | DCTPP1 (0.42) | DCTPP1 | |
| SCHEMBL7051965 | 0.68 | IDO1 (0.51) | IDO1GRM5HSD17B2 | |
| SCHEMBL7338245 | 0.66 | DCTPP1 (0.49) | IDO1DCTPP1TDO2PKMPTGS2 | |
| SCHEMBL20743882 | 0.66 | IDO1 (1.00) | IDO1TDO2 | |
| SCHEMBL1398873 | 0.64 | DCTPP1 (0.44) | IDO1DCTPP1PKMPTGS2 | |
| Methane SCHEMBL7899065 | 0.64 | DCTPP1 (0.40) | DCTPP1 | |
| SCHEMBL2686082 | 0.62 | IDO1 (0.44) | IDO1GRM5HSD17B2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | claimed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | claimed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | claimed |
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |